1894 The already famous octogenarian surgeon, Brown-Sequard claimed at a conference that by injecting himself with dog and monkey testicle infused water, he had revived himself from old age. He claimed that his pee stream got longer, that he regained his sex drive, and his mental clarity with it. We know now that this concoction would have carried no hormones since they're hydrophobic.

But regardless, his claims set off an age of what was termed organotherapy through the early 1900's in which testicles were surgically removed from animals and prisoners and reinserted into patients in an attempt to optimize the reproductive capacity of the nation, prolong lifelong productivity and performance of state sanctioned genders, and eliminate undesirable, deviant, queer, and gender nonconforming behaviors.